The manuscript collections in Atkins Library Special Collections and University Archives document the politics, people, arts and culture, social conditions, businesses, and activities of the Charlotte-Mecklenburg region. These archives date from the 19th to the 21st century, with the bulk representing the last half of the 20th century.

Manuscripts are original records that have been created or received by individuals, families, organizations, institutions, or agencies in the conduct of their affairs that document their transactions, ideas, decisions, or discussions. They may be in the form of correspondence, diaries, ledgers, memoranda, minutes, accounts, reports, literary creations, title deeds, legal documents, and photographs.